Courtney Lawes will start for England in their crunch Six Nations clash against Wales this weekend with head coach Eddie Jones today naming his squad to play in Cardiff.
The 29-year-old Northampton Saints lock is selected in the second row and will bring up his 71st cap in the Principality Stadium showdown, which kicks off at 4.45pm on Saturday.
Meanwhile fly-half Dan Biggar will look to make an impact off the bench after he was named amongst the Wales replacements by Warren Gatland.
Wales v England will be shown in the Rodber and Members bars at Franklin's Gardens following Saints' Gallagher Premiership clash against Bath Rugby, which kicks off at 2.45pm.
Jones said: “England and Wales is always a big game. Intense rivals and there is the historical context to it, but for us it is our most important game because it is our next game and that is how we are treating it.
“Whenever you play against a Warren Gatland side you are playing against a side that is going to be very physical on the gain line. They are always very fit so you have to make sure you win the gain line and then find opportunities of where you are going to attack them.
“As you have read in the media, it’s all about Wales, we are playing potentially the greatest team ever. Their players are full of emotion and it’s the biggest game they are going to play in their lives. We have had a good week just focussing on ourselves and focussing on getting our preparation right.”
Gatland added: “We are really happy with the experience we have got in the side. We have been on the road for the first two weeks, we are looking forward to being back at home and to build on those first two wins and to build on our performance.
“We know how important this game is for the rest of the championship. It's a massive challenge playing against an England team that is playing really well and with a lot of confidence and we've got to make it difficult for them on Saturday.
“We are looking forward to it and we know the Welsh fans are too and it's going to be a huge weekend in the Six Nations.”
England team to play Wales
15 Elliot Daly
14 Jack Nowell
13 Henry Slade
12 Manu Tuilagi
11 Jonny May
10 Owen Farrell (c)
9 Ben Youngs
1 Ben Moon
2 Jamie George
3 Kyle Sinckler
4 Courtney Lawes (Northampton Saints, 70 caps)
5 George Kruis
6 Mark Wilson
7 Tom Curry
8 Billy Vunipola
Replacements:
16 Luke Cowan-Dickie
17 Ellis Genge
18 Harry Williams
19 Joe Launchbury
20 Brad Shields
21 Dan Robson
22 George Ford
23 Joe Cokanasiga
Wales team to play England
15. Liam Williams
14. George North
13. Jonathan Davies
12. Hadleigh Parkes
11. Josh Adams
10. Gareth Anscombe
9. Gareth Davies
1. Rob Evans
2. Ken Owens
3. Tomas Francis
4. Cory Hill
5. Alun Wyn Jones (c)
6. Josh Navidi
7. Justin Tipuric
8. Ross Moriarty
Replacements:
16. Elliot Dee
17. Nicky Smith
18. Dillon Lewis
19. Adam Beard
20. Aaron Wainwright
21. Aled Davies
22. Dan Biggar (Northampton Saints, 67 Caps)
23. Owen Watkin